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Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn.
المؤلفون المشاركون
Mondal, Arijit
Karan, Sanjay Kumar
Singha, Tanushree
Rajalingam, D.
Maity, Tapan Kumar
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-29
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
In the present study, the hepatoprotective activity of ethanolic extracts of Cassia sophera Linn.
leaves was evaluated against carbon-tetrachloride- (CCl4-) induced hepatic damage in rats.
The extracts at doses of 200 and 400 mg/kg were administered orally once daily.
The hepatoprotection was assessed in terms of reduction in histological damage, changes in serum enzymes, serum glutamate oxaloacetate transaminase (AST), serum glutamate pyruvate transaminase (ALT), serum alkaline phosphatase (ALP), total bilirubin, and total protein levels.
The substantially elevated serum enzymatic levels of AST, ALT, ALP, and total bilirubin were restored towards the normalization significantly by the extracts.
The decreased serum total protein level was significantly normalized.
Silymarin was used as standard reference and exhibited significant hepatoprotective activity against carbon tetrachloride-induced hepatotoxicity in rats.
The biochemical observations were supplemented with histopathological examination of rat liver sections.
The results of this study strongly indicate that Cassia sophera leaves have potent hepatoprotective action against carbon tetrachloride-induced hepatic damage in rats.
This study suggests that possible activity may be due to the presence of flavonoids in the extracts.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mondal, Arijit& Karan, Sanjay Kumar& Singha, Tanushree& Rajalingam, D.& Maity, Tapan Kumar. 2012. Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn.. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-992291
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mondal, Arijit…[et al.]. Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn.. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-992291
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mondal, Arijit& Karan, Sanjay Kumar& Singha, Tanushree& Rajalingam, D.& Maity, Tapan Kumar. Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn.. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-992291
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992291
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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