Classification of Traditional Chinese Medicine Syndromes in Patients with Chronic Hepatitis B by SELDI-Based ProteinChip Analysis
المؤلفون المشاركون
Lu, Yi-yu
Hu, Yi-Yang
Zhang, Hui
Song, Ya-Nan
Guan, Yan
Peng, Jing-hua
Su, Shi-Bing
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Traditional Chinese medicine (TCM) syndrome, also called ZHENG, is the basis concept of TCM theory.
It plays an important role in TCM practice.
There are excess and deficiency syndromes in TCM syndrome.
They are the common syndromes in chronic hepatitis B (CHB) patients.
Here we aim to explore serum protein profiles and potential biomarkers for classification of TCM syndromes in CHB patients.
24 healthy controls and two cohorts of CHB patients of excess syndrome (n=25) or deficiency syndrome (n=19) were involved in this study.
Protein profiles were obtained by surface-enhanced laser desorption ionization time-flight mass spectrometry (SELDI-TOF/MS) and multiple analyses were performed.
Based on SELDI ProteinChip data, healthy controls and CHB patients or excess and deficiency syndromes in CHB patients were obviously differentiated by orthogonal partial least square (OPLS) analysis.
Two significant serum proteins (m/z 4187 and m/z 5032) for classifying excess and deficiency syndromes were found.
Moreover, the area under the receiver operating characteristic (ROC) curve was 0.887 for classifying excess and nonexcess syndrome, and 0.700 for classifying deficiency and nondeficiency syndrome, respectively.
Therefore, the present study provided the possibility of TCM syndrome classification in CHB patients using a universally acceptable scientific approach.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Song, Ya-Nan& Zhang, Hui& Guan, Yan& Peng, Jing-hua& Lu, Yi-yu& Hu, Yi-Yang…[et al.]. 2012. Classification of Traditional Chinese Medicine Syndromes in Patients with Chronic Hepatitis B by SELDI-Based ProteinChip Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992472
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Song, Ya-Nan…[et al.]. Classification of Traditional Chinese Medicine Syndromes in Patients with Chronic Hepatitis B by SELDI-Based ProteinChip Analysis. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-992472
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Song, Ya-Nan& Zhang, Hui& Guan, Yan& Peng, Jing-hua& Lu, Yi-yu& Hu, Yi-Yang…[et al.]. Classification of Traditional Chinese Medicine Syndromes in Patients with Chronic Hepatitis B by SELDI-Based ProteinChip Analysis. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992472
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992472
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر