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Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial
المؤلفون المشاركون
Jawad, M.
Schoop, R.
Suter, A.
Klein, P.
Eccles, R.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-16
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
To investigate the safety (risk) and efficacy (benefit) of Echinacea purpurea extract in the prevention of common cold episodes in a large population over a 4-month period.
Methods.
755 healthy subjects were allocated to receive either an alcohol extract from freshly harvested E.
purpurea (95% herba and 5% root) or placebo.
Participants were required to record adverse events and to rate cold-related issues in a diary throughout the investigation period.
Nasal secretions were sampled at acute colds and screened for viruses.
Results.
A total of 293 adverse events occurred with Echinacea and 306 with placebo treatment.
Nine and 10% of participants experienced adverse events, which were at least possibly related to the study drug (adverse drug reactions).
Thus, the safety of Echinacea was noninferior to placebo.
Echinacea reduced the total number of cold episodes, cumulated episode days within the group, and pain-killer medicated episodes.
Echinacea inhibited virally confirmed colds and especially prevented enveloped virus infections (P<0.05).
Echinacea showed maximal effects on recurrent infections, and preventive effects increased with therapy compliance and adherence to the protocol.
Conclusions.
Compliant prophylactic intake of E.
purpurea over a 4-month period appeared to provide a positive risk to benefit ratio.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jawad, M.& Schoop, R.& Suter, A.& Klein, P.& Eccles, R.. 2012. Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-992702
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jawad, M.…[et al.]. Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-992702
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jawad, M.& Schoop, R.& Suter, A.& Klein, P.& Eccles, R.. Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-992702
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992702
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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