Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.
المؤلفون المشاركون
Ong, Hui San
Firdaus-Raih, Mohd
Mohamed, Rahmah
المصدر
International Journal of Genomics
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-06
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Members of the Burkholderia family occupy diverse ecological niches.
In pathogenic family members, glycan-associated proteins are often linked to functions that include virulence, protein conformation maintenance, surface recognition, cell adhesion, and immune system evasion.
Comparative analysis of available Burkholderia genomes has revealed a core set of 178 glycan-associated proteins shared by all Burkholderia of which 68 are homologous to known essential genes.
The genome sequence comparisons revealed insights into species-specific gene acquisitions through gene transfers, identified an S-layer protein, and proposed that significantly reactive surface proteins are associated to sugar moieties as a potential means to circumvent host defense mechanisms.
The comparative analysis using a curated database of search queries enabled us to gain insights into the extent of conservation and diversity, as well as the possible virulence-associated roles of glycan-associated proteins in members of the Burkholderia spp.
The curated list of glycan-associated proteins used can also be directed to screen other genomes for glycan-associated homologs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ong, Hui San& Mohamed, Rahmah& Firdaus-Raih, Mohd. 2012. Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.. International Journal of Genomics،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-992915
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ong, Hui San…[et al.]. Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.. International Journal of Genomics No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-992915
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ong, Hui San& Mohamed, Rahmah& Firdaus-Raih, Mohd. Comparative Genome Sequence Analysis Reveals the Extent of Diversity and Conservation for Glycan-Associated Proteins in Burkholderia spp.. International Journal of Genomics. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-992915
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992915
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر