Impact of Diabetes and Hyperglycemia on Survival in Advanced Breast Cancer Patients
المؤلفون المشاركون
Ramirez-Morales, Rebeca
Aguila, Christian
Herrera, Luis A.
Lara-Medina, Fernando
Shaw-Dulin, Robin
Bacon, Ludwing
Rivera, Daniel
Villarreal-Garza, Cynthia
Santamaria, Julieta
Urzua, Lorena
Silvio, A. Ñamendys-Silva
Mohar, Alejandro
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
We examined the impact of diabetes and hyperglycemia on cancer-specific survival of patients with metastatic or recurrent breast cancer (BC).
Methods.
We performed a retrospective analysis of 265 patients with advanced BC receiving palliative chemotherapy.
BC-specific mortality was compared for diabetic and nondiabetic patients as well as for patients that presented hyperglycemia during treatment.
Results.
No difference was observed between the diabetic and nondiabetic patients in terms of overall survival (OS).
A difference in OS was observed between nondiabetic patients and diabetic patients who had hyperglycemia.
The OS was greater in diabetic patients with proper metabolic control than diabetic patients with hyperglycemia.
The risk of death was higher in patients with mean glucose levels >130 mg/dL during treatment.
Several factors were associated with poor OS: tumor stage, hormone-receptor-negative tumors, HER2 negative disease, multiple metastatic sites, presence of visceral metastases, and mean glucose >130 mg/dL.
Conclusion.
Elevated glucose levels are associated with a poor outcome in diabetic and nondiabetic patients in contrast to patients with normoglycemic levels, conferring an elevated risk of death.
According to these results, clinicians should monitor glucose levels during treatment for advanced breast cancer disease and take action to maintain normal glucose levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Villarreal-Garza, Cynthia& Shaw-Dulin, Robin& Lara-Medina, Fernando& Bacon, Ludwing& Rivera, Daniel& Urzua, Lorena…[et al.]. 2012. Impact of Diabetes and Hyperglycemia on Survival in Advanced Breast Cancer Patients. Journal of Diabetes Research،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-994066
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Villarreal-Garza, Cynthia…[et al.]. Impact of Diabetes and Hyperglycemia on Survival in Advanced Breast Cancer Patients. Journal of Diabetes Research Vol. 2012, no. 2012 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-994066
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Villarreal-Garza, Cynthia& Shaw-Dulin, Robin& Lara-Medina, Fernando& Bacon, Ludwing& Rivera, Daniel& Urzua, Lorena…[et al.]. Impact of Diabetes and Hyperglycemia on Survival in Advanced Breast Cancer Patients. Journal of Diabetes Research. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-994066
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-994066
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر