Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study
المؤلفون المشاركون
Narumi, Taro
Shibata, Yoko
Kato, Takeo
Arimoto, Takanori
Shishido, Tetsuro
Ueno, Yoshiyuki
Takahashi, Hiroki
Miyamoto, Takuya
Kiribayashi, Nobuyuki
Miyashita, Takehiko
Kadowaki, Shinpei
Kubota, Isao
Konta, Tsuneo
Watanabe, Tetsu
Nishiyama, Satoshi
Kayama, Takamasa
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-10-10
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Insulin resistance (IR) is part of the metabolic syndrome (Mets) that develops after lifestyle changes and obesity.
Although the association between Mets and myocardial injury is well known, the effect of IR on myocardial damage remains unclear.
Methods and Results.
We studied 2200 normal subjects who participated in a community-based health check in the town of Takahata in northern Japan.
The presence of IR was assessed by homeostasis model assessment ratio, and the serum level of heart-type fatty acid binding protein (H-FABP) was measured as a maker of silent and ongoing myocardial damage.
H-FABP levels were significantly higher in subjects with IR and Mets than in those without metabolic disorder regardless of gender.
Multivariate logistic analysis showed that the presence of IR was independently associated with latent myocardial damage (odds ratio: 1.574, 95% confidence interval 1.1–2.3) similar to the presence of Mets.
Conclusions.
In a screening of healthy subjects, IR and Mets were similarly related to higher H-FABP levels, suggesting that there may be an asymptomatic population in the early stages of metabolic disorder that is exposed to myocardial damage and might be susceptible to silent heart failure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Narumi, Taro& Shishido, Tetsuro& Kiribayashi, Nobuyuki& Kadowaki, Shinpei& Nishiyama, Satoshi& Takahashi, Hiroki…[et al.]. 2012. Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study. Journal of Diabetes Research،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-994091
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Narumi, Taro…[et al.]. Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study. Journal of Diabetes Research Vol. 2012, no. 2012 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-994091
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Narumi, Taro& Shishido, Tetsuro& Kiribayashi, Nobuyuki& Kadowaki, Shinpei& Nishiyama, Satoshi& Takahashi, Hiroki…[et al.]. Impact of Insulin Resistance on Silent and Ongoing Myocardial Damage in Normal Subjects: The Takahata Study. Journal of Diabetes Research. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-994091
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-994091
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر