Family History of Autoimmune Disease in Patients with Aicardi-Goutières Syndrome
المؤلفون المشاركون
Schmidt, Johanna L.
Vanderver, Adeline
Fazzi, Elisa
Vento, Jodie M.
Orcesi, Simona
Gordish-Dressman, Heather
Olivieri, Ivana
المصدر
Journal of Immunology Research
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-11
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
The purpose of this study was to explore anecdotal evidence for an increase in the prevalence of autoimmune diseases in family members of patients with Aicardi-Goutières syndrome (AGS).
Methods.
Pedigrees of patients and controls were analyzed using chi-square and logistic regression to assess differences in reports of autoimmune disease among family members of cases and controls.
Data was collected at Children's National Medical Center in Washington, DC, USA and at the International Aicardi-Goutières Syndrome Association Scientific Headquarters, C.
Mondino National Institute of Neurology in Pavia, Italy.
Results.
The number of individuals with reported autoimmune disease is significantly related to having a family member with AGS (χ2=6.25, P=0.01); 10% (35/320) of relatives of patients with AGS had a reported autoimmune disease diagnosis compared to 5% (18/344) of relatives of controls.
There was a greater percent of maternal relatives of patients with AGS reporting autoimmune disease (14.6%), compared to controls (6.8%), with the association being statistically significant.
The association was not significant for paternal relatives.
Conclusion.
The prevalence of autoimmune disease in relatives of children with AGS is significantly increased compared to controls.
More research is needed to better understand this association.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Schmidt, Johanna L.& Olivieri, Ivana& Vento, Jodie M.& Fazzi, Elisa& Gordish-Dressman, Heather& Orcesi, Simona…[et al.]. 2012. Family History of Autoimmune Disease in Patients with Aicardi-Goutières Syndrome. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-994369
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Schmidt, Johanna L.…[et al.]. Family History of Autoimmune Disease in Patients with Aicardi-Goutières Syndrome. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-994369
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Schmidt, Johanna L.& Olivieri, Ivana& Vento, Jodie M.& Fazzi, Elisa& Gordish-Dressman, Heather& Orcesi, Simona…[et al.]. Family History of Autoimmune Disease in Patients with Aicardi-Goutières Syndrome. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-994369
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-994369
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر