Magnetic Carbon Nanotubes for Protein Separation

الملخص EN

Magnetic separation is a promising strategy in protein separation.

Owing to their unique one-dimensional structures and desired magnetic properties, stacked-cup carbon nanotubes (CSCNTs) with magnetic nanoparticles trapped in their tips can serve as train-like systems for protein separation.

In this study, we functionalized the magnetic CSCNTs with high density of carboxyl groups by radical addition and then anchored 3-aminophenylboronic acid (APBA) through amidation reaction to achieve oriented conjunction of antibodies (IgG).

It was also demonstrated that the obtained magnetic CSCNTs-APBA-IgG conjugates could readily react with target antigens through specific antigen-antibody reaction and be used as new magnetic systems for protein separation.