Assessment of cytotoxic and anticancer activity of Zygophyllum album and Suaeda palastina extracts on human liver cancer cell lines

العناوين الأخرى

زيجوفلم ألبم و السويدة تقييم السمية الخلوية و النشاط المضاد للسرطان لمستخلصات على خطوط خلايا سرطان الكبد في الإنسان

المؤلفون المشاركون

Kamil, Hidayah Ahmad
Abd al-Tawwab, Fathi Muhammad
al-Attar, Marwah Mahmud
Awad, Abd al-Fattah Abd al-Qadir
Ahmad, Akram Salah al-Din
Hasan, Amal Ibrahim

المصدر

Arab Universities Journal of Agricultural Sciences

الناشر

جامعة عين شمس كلية الزراعة

تاريخ النشر

2019-03-31

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

العلوم الزراعية

الموضوعات

الملخص الإنجليزي

In this study, anticancer activity of Zygophyllum album and Suaeda palastina extracts was evaluated.

Dichloromethane, methanol and hot water were used as solvents for extraction.

Results indicated that the highest half-maximal inhibitory concentration (IC50) on human lung carcinoma (A549) cell lines was achieved by dichloromethane extracts of Z.

album and S.

palastina (70.48 μg/ml and 34.82 μg/ml respectively) compared to methanolic and hot water extracts.

Furthermore, dichloromethane extracts of both plants had antiproliferative effect and highly cytotoxicity on human cancer cells.

IC50 of Z.

album was 27.74 μg/ml in the human hepatocellular carcinoma (HepG2), while IC50 of S.

palaestina was 30.76 μg/ml with no cytotoxic activity on normal cell lines.

In conclusion, these results suggest that Z.

album and S.

palaestina could be a good candidate species as a natural source of anticancer agents.

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-999840

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

al-Attar, Marwah Mahmud& Awad, Abd al-Fattah Abd al-Qadir& Abd al-Tawwab, Fathi Muhammad& Kamil, Hidayah Ahmad& Ahmad, Akram Salah al-Din& Hasan, Amal Ibrahim. 2019-03-31. Assessment of cytotoxic and anticancer activity of Zygophyllum album and Suaeda palastina extracts on human liver cancer cell lines. . Vol. 27, no. 1 (s) (2019), pp.539-544.Cairo Egypt : Ain Shams University Faculty of Agriculture.
https://search.emarefa.net/detail/BIM-999840

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

al-Attar, Marwah Mahmud…[et al.]. Assessment of cytotoxic and anticancer activity of Zygophyllum album and Suaeda palastina extracts on human liver cancer cell lines. . Cairo Egypt : Ain Shams University Faculty of Agriculture. 2019-03-31.
https://search.emarefa.net/detail/BIM-999840

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

al-Attar, Marwah Mahmud& Awad, Abd al-Fattah Abd al-Qadir& Abd al-Tawwab, Fathi Muhammad& Kamil, Hidayah Ahmad& Ahmad, Akram Salah al-Din& Hasan, Amal Ibrahim. Assessment of cytotoxic and anticancer activity of Zygophyllum album and Suaeda palastina extracts on human liver cancer cell lines. .
https://search.emarefa.net/detail/BIM-999840