Synthesis, structural and biological studies of 3-(1, 3- benzothiazol-2-yl)‎ - 4H- spiro[indole2,3-[1,3]thiazolidine]- 2,4(1H)‎ dion with Cr (III)‎, Mn (II)‎, Co (II)‎, Ni (II)‎, Cu (II)‎, and Zn (II)‎ ions

Abstract EN

This paper describes the synthesis of a new derivative 3-(1, 3-benzothiazol-2-yl) / 4H- spiro[indole2,3-[1, 3] thiazolidine] -2, / 4 (1H) dion [L], which have been obtained from the cyclization of 3-(benzo [d] thiazol-2- ylimino) indolin -2-one[AB] through the addition of α-mercapto acetic acid.

The product [L] was characterized by (FT.IR) and (U.Vis) spectroscopy and in addition to element analysis (C.H.N.S.) A number of metal complexes were synthesized from the reaction of the ligand [L] with ions Cr (III), Mn (II), Co (II), Ni (II), Cu (II), and Zn (II).

The prepared complexes were isolated and characterized by using (FT.IR) and (U.Vis) spectroscopy in addition to element analysis (C.H.N.S.), flame atomic absorption technique, in addition to magnetic susceptibility and conductivity measurement.

The antibacterial activity of the ligand [L] and its complexes were studied against two selected micro-organisms (Pseudonomous aerugionosa) as gram negative and (Bacillus subtitis) as gram positive.