Synthesis and antibactrial study of new 2-Amino-5-Aryl- 1,3-Thiazole-4-Carboxylic acid derivatives
Other Title(s)
تحضير و دراسة الفعالية ضد البكتيريا لمركبات 2-أمنيو-5-اريل-3،1-ثايوزول-4-كاربو كسيليك اسد الجديدة
Joint Authors
Kazim, Uras Amin
al-Dulaymi, Zaynah Khudayr
Atiyyah, Abd al-Jabbar Khalaf
Thani, Muhammad Zabun
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 26, Issue 2 (31 Aug. 2013), pp.188-197, 10 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2013-08-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Topics
Abstract AR
حضر-2 أمينو-5-اريل -3,1- ثايوزول-4-كاربوكسيليك اسد (A1-A3) من تفاعل الديهايدات اروماتية مختلفة مع ثنائي كلورو حامض الخليك و الثايويوريا.
كما حضرت المركبات (A22-A30) مبتدئا من المركبات الأساس (A1-A3) و بخطوتين باستخدام قواعد شف (A4-A12) المحضرة من تفاعل المركبات (A1-A3) مع الديهايدات اروماتية مختلفة.
و أخيرا حضر نوعان من الايمايدات من تفاعل (A1-A3) مع انهيدريد الماليك (A31-A33) و انهيدريد الفثاليك (A34-A36) بوجود حامض الخليك الثلجي.
شخصت المركبات المحضرة باستخدام طيف الأشعة تحت الحمراء (FT-IR) و الأشعة فوق البنفسجية (UV-Visible).
Abstract EN
-2 Amino-5-aryl- 1, 3-thiazole-4-carboxylic acid (A1-A3) were synthesized from the reaction of various aromatic aldehyde with dichloro acetic acid and thiourea.
The synthesis of 2- [(S-aminosulfinim-idoyl) (aryl) methyl] (benzoyl) amino] -5-aryl-1, 3-thiazole-4-carboxylic acid (A22-A30) was perfomed starting from (A1-A3) by two steps using Schiff's base (A4-A12) prepared from the reactant compounds (A1-A3) with different aromatic aldehyde.
Finally two types of imide derivatives were obtained from reactant compounds (A1-A3) with malic anhydride (A31-A33) and phthalic anhydride (A34-A36) in the presence of glacial acetic acid.
All proposed structures were supported by FT-IR and UV-Visible spectroscopic data.
American Psychological Association (APA)
al-Dulaymi, Zaynah Khudayr& Kazim, Uras Amin& Atiyyah, Abd al-Jabbar Khalaf& Thani, Muhammad Zabun. 2013. Synthesis and antibactrial study of new 2-Amino-5-Aryl- 1,3-Thiazole-4-Carboxylic acid derivatives. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 26, no. 2, pp.188-197.
https://search.emarefa.net/detail/BIM-342389
Modern Language Association (MLA)
al-Dulaymi, Zaynah Khudayr…[et al.]. Synthesis and antibactrial study of new 2-Amino-5-Aryl- 1,3-Thiazole-4-Carboxylic acid derivatives. Ibn al-Haitham Journal for Pure and Applied Science Vol. 26, no. 2 (Aug. 2013), pp.188-197.
https://search.emarefa.net/detail/BIM-342389
American Medical Association (AMA)
al-Dulaymi, Zaynah Khudayr& Kazim, Uras Amin& Atiyyah, Abd al-Jabbar Khalaf& Thani, Muhammad Zabun. Synthesis and antibactrial study of new 2-Amino-5-Aryl- 1,3-Thiazole-4-Carboxylic acid derivatives. Ibn al-Haitham Journal for Pure and Applied Science. 2013. Vol. 26, no. 2, pp.188-197.
https://search.emarefa.net/detail/BIM-342389
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 193-196
Record ID
BIM-342389
