تأثير استخدام حليب الأفراس المخمر في شفاء قرحة المعدة المستحدثة بالأسبرين في الجرذان البيضاء

Abstract EN

This study was conducted in the animal houses of veterinary medicine college/AL-Qadisiya university during the period from 27-2-2014 to 30-3-2014, to study the effect of using fermented mares milk on the healing of gastric ulcer that induced by aspirin in albino rats.

A total of 56 albino female rats were used in this study the rats were divided randomly in to four groups each group containing 14 rats; Negative control group (C) that was fed only basal diet and distilled water.

Positive control group (T1) that induced gastric ulcer by aspirin (100mg/kg B.W) for 7 days.

Second treated group (T2) that induced gastric ulcer by aspirin for 7days then was orally treated with fermented mares milk (10ml/kg B.W) for 21days.The third treated group (T3) that induced gastric ulcer by aspirin then was orally treated with ranitidine 50mg/kg B.W) for 21days.

The result of the current study showed that the aspirin had a significantly effect (p<0.05) on ulcer parameters, formation many ulcers in gastric mucosa increased ulcer score and ulcer index and decrease the pH of gastric juice.

The result also showed that fermented mares milk significantly (P<0.05) influenced the ulcer parameter as compared to the aspirin group and their values were closely with values of the control group and the ranitidine group, According to the result we concluded that fermented mares milk played an important role in healing of gastric ulcer as in ranitidine.