Spectrophotometric estimation of thiamine in tablet form application to content uniformity testing
Other Title(s)
تقدير الثيامين طيفيا في مستحضراته الصيدلانية : تطبيق الطريقة لاختبار الاتساق
Joint Authors
al-Qazzaz, Wail A.
Ahmad, Nayif Rahman
Source
Publisher
University of Mosul College of Science
Publication Date
2019-04-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
English Abstract
A simple, rapid, accurate and sensitive spectrophotometric method for the determination of thiamine has been developed.
The method is based on the direct reaction between thiamine and sodium hydroxide to produce a yellow colored product having maximum absorption at 335 nm.
Beer's law was obeyed over the concentration range of 2-20μg/ml,with molar absorptivity of 1.58x104 l/mol.cm.
The present method was considered to be simple because it does not need heating, hydrolysis and solvent extraction steps.
The ingredients often formulated with thiamine, have been shown not to interfere, and is suitable for the routine determination of thiamine.
The proposed method has been successfully applied for the determination of thiamine in pure form and in pharmaceutical preparations(tablets).
Data Type
Conference Papers
Record ID
BIM-895002
American Psychological Association (APA)
Ahmad, Nayif Rahman& al-Qazzaz, Wail A.. 2019-04-30. Spectrophotometric estimation of thiamine in tablet form application to content uniformity testing. Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya). . Vol. 28, no. 2 (Special issue) (2019), pp.146-151.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-895002
Modern Language Association (MLA)
Ahmad, Nayif Rahman& al-Qazzaz, Wail A.. Spectrophotometric estimation of thiamine in tablet form application to content uniformity testing. . Mosul Iraq : University of Mosul College of Science. 2019-04-30.
https://search.emarefa.net/detail/BIM-895002
American Medical Association (AMA)
Ahmad, Nayif Rahman& al-Qazzaz, Wail A.. Spectrophotometric estimation of thiamine in tablet form application to content uniformity testing. . Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya).
https://search.emarefa.net/detail/BIM-895002
