Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals

Joint Authors

Popa, Calin D.
Arts, Elke
Fransen, Jaap
van Riel, Piet L. C. M.

Source

Mediators of Inflammation

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-09-06

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Diseases

Abstract EN

Cardiovascular (CV) diseases are a serious concern in rheumatoid arthritis (RA), accounting for approximately one-third to one-half of all RA-related deaths.

Besides the attempts to identify new risk factors, the proper management of traditional CV risk factors such as dyslipidemia should become a priority in the periodic evaluation of every RA patient.

Atherogenic index has been suggested to be less susceptible to disease activity variation during large periods of time, making him more attractive to be used in CV risk prediction in this group of patients as compared to individual lipids concentrations.

Nevertheless, inflammation may negatively impact HDL antiatherogenic properties, suggesting that HDL function assessment is of particular importance when predicting CV risk in these patients.

A tight control of inflammation becomes therefore crucial for a successful CV risk management.

The present paper debates these hypotheses focusing on the effects of therapy with biologicals on the above mentioned parameters.

American Psychological Association (APA)

Popa, Calin D.& Arts, Elke& Fransen, Jaap& van Riel, Piet L. C. M.. 2012. Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1001223

Modern Language Association (MLA)

Popa, Calin D.…[et al.]. Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals. Mediators of Inflammation No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1001223

American Medical Association (AMA)

Popa, Calin D.& Arts, Elke& Fransen, Jaap& van Riel, Piet L. C. M.. Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1001223

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1001223