Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age
Joint Authors
Balin, Mehmet
Çelik, Ahmet
Kobat, M. Ali
Baydas, Adil
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
It is known that menopause or lack of endogenous estrogen is a risk factor for endothelial dysfunction and CAD.
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is involved inmultiple phases of vascular dysfunction.The purpose of the current study was to determine the association between soluble LOX-1 (sLOX-1) and pregnancy followed by delivery in women of reproductive age.
Materials/Methods.
Sixty-eight subjects with pregnancy followed by delivery (group 1) and 57 subjects with nongravidity (group 2) were included in this study.
Levels of sLOX-1 were measured in serum by EL SA.
Results.
Plasma levels of sLOX-1 were significantly lower in Group 1 than Group 2 in women of reproductive age (0.52±0.18 ng/mL and 0.78±0.13, resp., P<0.001).
There were strong correlations between sLOX-1 levels and the number of gravida (r=−0.645, P<0.001).
The levels of sLOX-1 highly correlated with the number of parous (r=−0.683, P<0.001).
Conclusion.
Our study demonstrated that serum sLOX-1 levels were associated with pregnancy followed by delivery that might predict endothelial dysfunction.
We conclude that pregnancy followed by delivery may delay the beginning and progress of arteriosclerosis and its clinical manifestations in women of reproductive age.
American Psychological Association (APA)
Balin, Mehmet& Çelik, Ahmet& Kobat, M. Ali& Baydas, Adil. 2012. Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age. Mediators of Inflammation،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1001238
Modern Language Association (MLA)
Balin, Mehmet…[et al.]. Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age. Mediators of Inflammation No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1001238
American Medical Association (AMA)
Balin, Mehmet& Çelik, Ahmet& Kobat, M. Ali& Baydas, Adil. Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age. Mediators of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1001238
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1001238