Time to Be SHY? Some Comments on Sleep and Synaptic Homeostasis
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-29
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Sleep must serve an essential, universal function, one that offsets the risk of being disconnected from the environment.
The synaptic homeostasis hypothesis (SHY) is an attempt to identify this essential function.
Its core claim is that sleep is needed to reestablish synaptic homeostasis, which is challenged by the remarkable plasticity of the brain.
In other words, sleep is “the price we pay for plasticity.” In this issue, M.
G.
Frank reviewed several aspects of the hypothesis and raised several issues.
The comments below provide a brief summary of the motivations underlying SHY and clarify that SHY is a hypothesis not about specific mechanisms, but about a universal, essential function of sleep.
This function is the preservation of synaptic homeostasis in the face of a systematic bias toward a net increase in synaptic strength—a challenge that is posed by learning during adult wake, and by massive synaptogenesis during development.
American Psychological Association (APA)
Tononi, Giulio& Cirelli, Chiara. 2012. Time to Be SHY? Some Comments on Sleep and Synaptic Homeostasis. Neural Plasticity،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1002411
Modern Language Association (MLA)
Tononi, Giulio& Cirelli, Chiara. Time to Be SHY? Some Comments on Sleep and Synaptic Homeostasis. Neural Plasticity No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-1002411
American Medical Association (AMA)
Tononi, Giulio& Cirelli, Chiara. Time to Be SHY? Some Comments on Sleep and Synaptic Homeostasis. Neural Plasticity. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1002411
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1002411