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FDG PETCT in Initial Staging of Adult Soft-Tissue Sarcoma
Joint Authors
Freeman, Carolyn R.
Alabed, Yazan Z.
Hickeson, Marc
Roberge, David
Turcotte, Robert E.
Vakilian, Siavosh
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Soft-tissue sarcomas spread predominantly to the lung and it is unclear how often FDG-PET scans will detect metastases not already obvious by chest CT scan or clinical examination.
Adult limb and body wall soft-tissue sarcoma cases were identified retrospectively.
Ewing’s sarcoma, rhabdomyosarcoma, GIST, desmoid tumors, visceral tumors, bone tumors, and retroperitoneal sarcomas were excluded as were patients imaged for followup, response assessment, or recurrence.
All patients had a diagnostic chest CT scan.
109 patients met these criteria, 87% of which had intermediate or high-grade tumors.
The most common pathological diagnoses were leiomyosarcoma (17%), liposarcoma (17%), and undifferentiated or pleomorphic sarcoma (16%).
98% of previously unresected primary tumors were FDG avid.
PET scans were negative for distant disease in 91/109 cases.
The negative predictive value was 89%.
Fourteen PET scans were positive.
Of these, 6 patients were already known to have metastases, 3 were false positives, and 5 represented new findings of metastasis (positive predictive value 79%).
In total, 5 patients were upstaged by FDG-PET (4.5%).
Although PET scans may be of use in specific circumstances, routine use of FDG PET imaging as part of the initial staging of soft-tissue sarcomas was unlikely to alter management in our series.
American Psychological Association (APA)
Roberge, David& Vakilian, Siavosh& Alabed, Yazan Z.& Turcotte, Robert E.& Freeman, Carolyn R.& Hickeson, Marc. 2012. FDG PETCT in Initial Staging of Adult Soft-Tissue Sarcoma. Complexity،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1002939
Modern Language Association (MLA)
Roberge, David…[et al.]. FDG PETCT in Initial Staging of Adult Soft-Tissue Sarcoma. Complexity No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-1002939
American Medical Association (AMA)
Roberge, David& Vakilian, Siavosh& Alabed, Yazan Z.& Turcotte, Robert E.& Freeman, Carolyn R.& Hickeson, Marc. FDG PETCT in Initial Staging of Adult Soft-Tissue Sarcoma. Complexity. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-1002939
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1002939