Neural Crest Stem Cells from Dental Tissues: A New Hope for Dental and Neural Regeneration
Joint Authors
Ibarretxe, Gaskon
Crende, Olatz
Aurrekoetxea, Maitane
García-Murga, Victoria
Etxaniz, Javier
Unda, Fernando
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-04
Country of Publication
Egypt
No. of Pages
12
Abstract EN
Several stem cell sources persist in the adult human body, which opens the doors to both allogeneic and autologous cell therapies.
Tooth tissues have proven to be a surprisingly rich and accessible source of neural crest-derived ectomesenchymal stem cells (EMSCs), which may be employed to repair disease-affected oral tissues in advanced regenerative dentistry.
Additionally, one area of medicine that demands intensive research on new sources of stem cells is nervous system regeneration, since this constitutes a therapeutic hope for patients affected by highly invalidating conditions such as spinal cord injury, stroke, or neurodegenerative diseases.
However, endogenous adult sources of neural stem cells present major drawbacks, such as their scarcity and complicated obtention.
In this context, EMSCs from dental tissues emerge as good alternative candidates, since they are preserved in adult human individuals, and retain both high proliferation ability and a neural-like phenotype in vitro.
In this paper, we discuss some important aspects of tissue regeneration by cell therapy and point out some advantages that EMSCs provide for dental and neural regeneration.
We will finally review some of the latest research featuring experimental approaches and benefits of dental stem cell therapy.
American Psychological Association (APA)
Ibarretxe, Gaskon& Crende, Olatz& Aurrekoetxea, Maitane& García-Murga, Victoria& Etxaniz, Javier& Unda, Fernando. 2012. Neural Crest Stem Cells from Dental Tissues: A New Hope for Dental and Neural Regeneration. Stem Cells International،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1002941
Modern Language Association (MLA)
Ibarretxe, Gaskon…[et al.]. Neural Crest Stem Cells from Dental Tissues: A New Hope for Dental and Neural Regeneration. Stem Cells International No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-1002941
American Medical Association (AMA)
Ibarretxe, Gaskon& Crende, Olatz& Aurrekoetxea, Maitane& García-Murga, Victoria& Etxaniz, Javier& Unda, Fernando. Neural Crest Stem Cells from Dental Tissues: A New Hope for Dental and Neural Regeneration. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-1002941
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1002941