Tissue Engineering Strategies in Ligament Regeneration
Joint Authors
Huri, Gazi
Yilgor, Caglar
Yilgor Huri, Pinar
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-12-25
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Ligaments are dense fibrous connective tissues that connect bones to other bones and their injuries are frequently encountered in the clinic.
The current clinical approaches in ligament repair and regeneration are limited to autografts, as the gold standard, and allografts.
Both of these techniques have their own drawbacks that limit the success in clinical setting; therefore, new strategies are being developed in order to be able to solve the current problems of ligament grafting.
Tissue engineering is a novel promising technique that aims to solve these problems, by producing viable artificial ligament substitutes in the laboratory conditions with the potential of transplantation to the patients with a high success rate.
Direct cell and/or growth factor injection to the defect site is another current approach aiming to enhance the repair process of the native tissue.
This review summarizes the current approaches in ligament tissue engineering strategies including the use of scaffolds, their modification techniques, as well as the use of bioreactors to achieve enhanced regeneration rates, while also discussing the advances in growth factor and cell therapy applications towards obtaining enhanced ligament regeneration.
American Psychological Association (APA)
Yilgor, Caglar& Yilgor Huri, Pinar& Huri, Gazi. 2011. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells International،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1002986
Modern Language Association (MLA)
Yilgor, Caglar…[et al.]. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells International No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1002986
American Medical Association (AMA)
Yilgor, Caglar& Yilgor Huri, Pinar& Huri, Gazi. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells International. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1002986
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1002986