Tissue Engineering Strategies in Ligament Regeneration

Joint Authors

Huri, Gazi
Yilgor, Caglar
Yilgor Huri, Pinar

Source

Stem Cells International

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-12-25

Country of Publication

Egypt

No. of Pages

9

Abstract EN

Ligaments are dense fibrous connective tissues that connect bones to other bones and their injuries are frequently encountered in the clinic.

The current clinical approaches in ligament repair and regeneration are limited to autografts, as the gold standard, and allografts.

Both of these techniques have their own drawbacks that limit the success in clinical setting; therefore, new strategies are being developed in order to be able to solve the current problems of ligament grafting.

Tissue engineering is a novel promising technique that aims to solve these problems, by producing viable artificial ligament substitutes in the laboratory conditions with the potential of transplantation to the patients with a high success rate.

Direct cell and/or growth factor injection to the defect site is another current approach aiming to enhance the repair process of the native tissue.

This review summarizes the current approaches in ligament tissue engineering strategies including the use of scaffolds, their modification techniques, as well as the use of bioreactors to achieve enhanced regeneration rates, while also discussing the advances in growth factor and cell therapy applications towards obtaining enhanced ligament regeneration.

American Psychological Association (APA)

Yilgor, Caglar& Yilgor Huri, Pinar& Huri, Gazi. 2011. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells International،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1002986

Modern Language Association (MLA)

Yilgor, Caglar…[et al.]. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells International No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-1002986

American Medical Association (AMA)

Yilgor, Caglar& Yilgor Huri, Pinar& Huri, Gazi. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells International. 2011. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-1002986

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1002986