Regulation of Injury-Induced Neurogenesis by Nitric Oxide
Joint Authors
Carreira, Bruno P.
Carvalho, Caetana M.
Araújo, Inês M.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-10
Country of Publication
Egypt
No. of Pages
15
Abstract EN
The finding that neural stem cells (NSCs) are able to divide, migrate, and differentiate into several cellular types in the adult brain raised a new hope for restorative neurology.
Nitric oxide (NO), a pleiotropic signaling molecule in the central nervous system (CNS), has been described to be able to modulate neurogenesis, acting as a pro- or antineurogenic agent.
Some authors suggest that NO is a physiological inhibitor of neurogenesis, while others described NO to favor neurogenesis, particularly under inflammatory conditions.
Thus, targeting the NO system may be a powerful strategy to control the formation of new neurons.
However, the exact mechanisms by which NO regulates neural proliferation and differentiation are not yet completely clarified.
In this paper we will discuss the potential interest of the modulation of the NO system for the treatment of neurodegenerative diseases or other pathological conditions that may affect the CNS.
American Psychological Association (APA)
Carreira, Bruno P.& Carvalho, Caetana M.& Araújo, Inês M.. 2012. Regulation of Injury-Induced Neurogenesis by Nitric Oxide. Stem Cells International،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-1003117
Modern Language Association (MLA)
Carreira, Bruno P.…[et al.]. Regulation of Injury-Induced Neurogenesis by Nitric Oxide. Stem Cells International No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-1003117
American Medical Association (AMA)
Carreira, Bruno P.& Carvalho, Caetana M.& Araújo, Inês M.. Regulation of Injury-Induced Neurogenesis by Nitric Oxide. Stem Cells International. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-1003117
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003117