Illuminating the Petite Picture of T Cell Memory Responses to Listeria monocytogenes
Joint Authors
Tufail, Saba
Badrealam, Khan Farheen
Zubair, Swaleha
Owais, Mohammad
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The ease to culture, moderately less safety constraints in handling, and above all, hurdle free induction of an anticipated infection in mouse rendered Listeria monocytogenes the rank of a model organism for studying a variety of host immune responses.
Listeria monocytogenes being an intracellular pathogen evokes potent CD8 T cell response during which CD8 T cells pass through a massive expansion phase.
This is generally followed by contraction phase wherein majority of activated cells undergo apoptosis leaving behind a population of memory CD8 T cells that has potential to confer enhanced protection upon reencounter with the same pathogen.
Functional attributes of various cytokines, transcription factors, receptors, adaptors, and effectors pertaining to the generation of robust memory T cell response have begun to be unravelled for better understanding of memory and opening avenues to create superior vaccine strategies.
This review is an attempt to unveil related discoveries along with updating recent advances on this issue.
American Psychological Association (APA)
Tufail, Saba& Badrealam, Khan Farheen& Owais, Mohammad& Zubair, Swaleha. 2013. Illuminating the Petite Picture of T Cell Memory Responses to Listeria monocytogenes. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1003275
Modern Language Association (MLA)
Tufail, Saba…[et al.]. Illuminating the Petite Picture of T Cell Memory Responses to Listeria monocytogenes. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1003275
American Medical Association (AMA)
Tufail, Saba& Badrealam, Khan Farheen& Owais, Mohammad& Zubair, Swaleha. Illuminating the Petite Picture of T Cell Memory Responses to Listeria monocytogenes. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1003275
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003275