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Inflammation and Immunity in Radiation Damage to the Gut Mucosa
Joint Authors
François, Agnès
Milliat, Fabien
Guipaud, Olivier
Benderitter, Marc
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Erythema was observed on the skin of the first patients treated with radiation therapy.
It is in particular to reduce this erythema, one feature of tissue inflammation, that prescribed dose to the tumor site started to be fractionated.
It is now well known that radiation exposure of normal tissues generates a sustained and apparently uncontrolled inflammatory process.
Radiation-induced inflammation is always observed, often described, sometimes partly explained, but still today far from being completely understood.
The thing with the gut and especially the gut mucosa is that it is at the frontier between the external milieu and the organism, is in contact with a plethora of commensal and foreign antigens, possesses a dense-associated lymphoid tissue, and is particularly radiation sensitive because of a high mucosal turnover rate.
All these characteristics make the gut mucosa a strong responsive organ in terms of radiation-induced immunoinflammation.
This paper will focus on what has been observed in the normal gut and what remains to be done concerning the immunoinflammatory response following localized radiation exposure.
American Psychological Association (APA)
François, Agnès& Milliat, Fabien& Guipaud, Olivier& Benderitter, Marc. 2013. Inflammation and Immunity in Radiation Damage to the Gut Mucosa. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1003278
Modern Language Association (MLA)
François, Agnès…[et al.]. Inflammation and Immunity in Radiation Damage to the Gut Mucosa. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1003278
American Medical Association (AMA)
François, Agnès& Milliat, Fabien& Guipaud, Olivier& Benderitter, Marc. Inflammation and Immunity in Radiation Damage to the Gut Mucosa. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1003278
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003278