Impact of Cardiovascular Organ Damage on Cortical Renal Perfusion in Patients with Chronic Renal Failure
Joint Authors
Lubas, Arkadiusz
Ryczek, Robert
Kade, Grzegorz
Smoszna, Jerzy
Niemczyk, Stanisław
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Properly preserved renal perfusion is the basic determinant of oxygenation, vitality, nutrition, and organ function and its structure.
Perfusion disorders are functional changes and are ahead of the appearance of biochemical markers of organ damage.
The aim of this study was to evaluate a relationship between the renal cortex perfusion and markers of cardiovascular organ damage in patients with stable chronic renal failure (CKD).
Methods.
Seventeen patients (2 F; 15 M; age 47±16) with stable CKD at 2–4 stages and hypertension or signs of heart failure were enrolled in this study.
Blood tests with an estimation of renal and cardiac functions, echocardiographic parameters, intima-media thickness (IMT), renal resistance index (RRI), and total (TPI), proximal (PPI), and distal (DPI) renal cortical perfusion intensity measurements were collected.
Results.
DPI was significantly lower than PPI.
TPI significantly correlated with age, Cys, CKD-EPI (cystatin), and IMT, whereas DPI significantly depended on Cystain, CKD-EPI (cystatin; cystatin-creatinine), IMT, NT-proBNP, and troponin I.
In multiple stepwise regression analysis model only CKD-EPI (cystatin) independently influenced DPI.
Conclusions.
Cardiovascular and kidney damage significantly influences renal cortical perfusion.
Ultrasound measurement of renal perfusion could be a sensitive method for early investigation of cardiovascular and renal injuries.
American Psychological Association (APA)
Lubas, Arkadiusz& Ryczek, Robert& Kade, Grzegorz& Smoszna, Jerzy& Niemczyk, Stanisław. 2013. Impact of Cardiovascular Organ Damage on Cortical Renal Perfusion in Patients with Chronic Renal Failure. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1003347
Modern Language Association (MLA)
Lubas, Arkadiusz…[et al.]. Impact of Cardiovascular Organ Damage on Cortical Renal Perfusion in Patients with Chronic Renal Failure. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1003347
American Medical Association (AMA)
Lubas, Arkadiusz& Ryczek, Robert& Kade, Grzegorz& Smoszna, Jerzy& Niemczyk, Stanisław. Impact of Cardiovascular Organ Damage on Cortical Renal Perfusion in Patients with Chronic Renal Failure. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1003347
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003347