Characterization and In Vivo Biological Performance of Biosilicate
Joint Authors
Renno, Ana Claudia M.
Bossini, Paulo Sérgio
Crovace, Murilo C.
Rodrigues, Ana Candida M.
Zanotto, Edgar Dutra
Parizotto, Nivaldo Antonio
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
After an introduction showing the growing interest in glasses and glass-ceramics as biomaterials used for bone healing, we describe a new biomaterial named Biosilicate.
Biosilicate is the designation of a group of fully crystallized glass-ceramics of the Na2O-CaO-SiO2-P2O5 system.
Several in vitro tests have shown that Biosilicate is a very active biomaterial and that the HCA layer is formed in less than 24 hours of exposure to “simulated body fluid” (SBF) solution.
Also, in vitro studies with osteoblastic cells have shown that Biosilicate disks supported significantly larger areas of calcified matrix compared to 45S5 Bioglass, indicating that this bioactive glass-ceramic may promote enhancement of in vitro bone-like tissue formation in osteogenic cell cultures.
Finally, due to its special characteristics, Biosilicate has also been successfully tested in several in vivo studies.
These studies revealed that the material is biocompatible, presents excellent bioactive properties, and is effective to stimulate the deposition of newly formed bone in animal models.
All these data highlight the huge potential of Biosilicate to be used in bone regeneration applications.
American Psychological Association (APA)
Renno, Ana Claudia M.& Bossini, Paulo Sérgio& Crovace, Murilo C.& Rodrigues, Ana Candida M.& Zanotto, Edgar Dutra& Parizotto, Nivaldo Antonio. 2013. Characterization and In Vivo Biological Performance of Biosilicate. BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1003379
Modern Language Association (MLA)
Renno, Ana Claudia M.…[et al.]. Characterization and In Vivo Biological Performance of Biosilicate. BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1003379
American Medical Association (AMA)
Renno, Ana Claudia M.& Bossini, Paulo Sérgio& Crovace, Murilo C.& Rodrigues, Ana Candida M.& Zanotto, Edgar Dutra& Parizotto, Nivaldo Antonio. Characterization and In Vivo Biological Performance of Biosilicate. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1003379
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003379