Innate Immunity Modulation by the IL-33ST2 System in Intestinal Mucosa
Joint Authors
García-Miguel, Marina
González, M. Julieta
Quera, Rodrigo
Hermoso, Marcela A.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-04
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Innate immunity prevents pathogens from entering and spreading within the body.
This function is especially important in the gastrointestinal tract and skin, as these organs have a large surface contact area with the outside environment.
In the intestine, luminal commensal bacteria are necessary for adequate food digestion and play a crucial role in tolerance to benign antigens.
Immune system damage can create an intestinal inflammatory response, leading to chronic disease including inflammatory bowel diseases (IBD).
Ulcerative colitis (UC) is an IBD of unknown etiology with increasing worldwide prevalence.
In the intestinal mucosa of UC patients, there is an imbalance in the IL-33/ST2 axis, an important modulator of the innate immune response.
This paper reviews the role of the IL-33/ST2 system in innate immunity of the intestinal mucosa and its importance in inflammatory bowel diseases, especially ulcerative colitis.
American Psychological Association (APA)
García-Miguel, Marina& González, M. Julieta& Quera, Rodrigo& Hermoso, Marcela A.. 2012. Innate Immunity Modulation by the IL-33ST2 System in Intestinal Mucosa. BioMed Research International،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1003382
Modern Language Association (MLA)
García-Miguel, Marina…[et al.]. Innate Immunity Modulation by the IL-33ST2 System in Intestinal Mucosa. BioMed Research International No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-1003382
American Medical Association (AMA)
García-Miguel, Marina& González, M. Julieta& Quera, Rodrigo& Hermoso, Marcela A.. Innate Immunity Modulation by the IL-33ST2 System in Intestinal Mucosa. BioMed Research International. 2012. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-1003382
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003382