Structures and Properties of Naturally Occurring Polyether Antibiotics
Joint Authors
Rutkowski, Jacek
Brzezinski, Bogumil
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-31, 31 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-17
Country of Publication
Egypt
No. of Pages
31
Main Subjects
Abstract EN
Polyether ionophores represent a large group of natural, biologically active substances produced by Streptomyces spp.
They are lipid soluble and able to transport metal cations across cell membranes.
Several of polyether ionophores are widely used as growth promoters in veterinary.
Polyether antibiotics show a broad spectrum of bioactivity ranging from antibacterial, antifungal, antiparasitic, antiviral, and tumour cell cytotoxicity.
Recently, it has been shown that some of these compounds are able to selectively kill cancer stem cells and multidrug-resistant cancer cells.
Thus, they are recognized as new potential anticancer drugs.
The biological activity of polyether ionophores is strictly connected with their molecular structure; therefore, the purpose of this paper is to present an overview of their formula, molecular structure, and properties.
American Psychological Association (APA)
Rutkowski, Jacek& Brzezinski, Bogumil. 2013. Structures and Properties of Naturally Occurring Polyether Antibiotics. BioMed Research International،Vol. 2013, no. 2013, pp.1-31.
https://search.emarefa.net/detail/BIM-1003576
Modern Language Association (MLA)
Rutkowski, Jacek& Brzezinski, Bogumil. Structures and Properties of Naturally Occurring Polyether Antibiotics. BioMed Research International No. 2013 (2013), pp.1-31.
https://search.emarefa.net/detail/BIM-1003576
American Medical Association (AMA)
Rutkowski, Jacek& Brzezinski, Bogumil. Structures and Properties of Naturally Occurring Polyether Antibiotics. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-31.
https://search.emarefa.net/detail/BIM-1003576
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003576