Clinical Evaluation and Cost-Effectiveness Analysis of Serum Tumor Markers in Lung Cancer
Joint Authors
Wang, Rong
Wang, Guoqing
Zhang, Nan
Li, Xue
Liu, Yunde
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The detection of serum tumor markers is valuable for the early diagnosis of lung cancer.
Tumor markers are frequently used for the management of cancer patients.
However, single markers are less efficient but marker combinations increase the cost, which is troublesome for clinics.
To find an optimal serum marker combination panel that benefits the patients and the medical management system as well, four routine lung cancer serum markers (SCCA, NSE, CEA, and CYFRA21-1) were evaluated individually and in combination.
Meanwhile, the costs and effects of these markers in clinical practice in China were assessed by cost-effectiveness analysis.
As expected, combinations of these tumor markers improved their sensitivity for lung cancer and different combination panels had their own usefulness.
NSE + CEA + CYFRA21-1 was the optimal combination panel with highest Youden’s index (0.64), higher sensitivity (75.76%), and specificity (88.57%), which can aid the clinical diagnosis of lung cancer.
Nevertheless, the most cost-effective combination was SCCA + CEA, which can be used to screen the high-risk group.
American Psychological Association (APA)
Wang, Rong& Wang, Guoqing& Zhang, Nan& Li, Xue& Liu, Yunde. 2013. Clinical Evaluation and Cost-Effectiveness Analysis of Serum Tumor Markers in Lung Cancer. BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1003676
Modern Language Association (MLA)
Wang, Rong…[et al.]. Clinical Evaluation and Cost-Effectiveness Analysis of Serum Tumor Markers in Lung Cancer. BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1003676
American Medical Association (AMA)
Wang, Rong& Wang, Guoqing& Zhang, Nan& Li, Xue& Liu, Yunde. Clinical Evaluation and Cost-Effectiveness Analysis of Serum Tumor Markers in Lung Cancer. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1003676
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003676