The Role of Morphine in Animal Models of Human Cancer: Does Morphine Promote or Inhibit the Tumor Growth?
Joint Authors
Bimonte, Sabrina
Barbieri, Antonio
Palma, Giuseppe
Arra, Claudio
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-27
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Morphine, a highly potent analgesic agent, is widely used to relieve pain and suffering of patients with cancer.
Additionally, it has been reported that morphine is important in the regulation of cancerous tissue.
Morphine relieves pain by acting directly on the central nervous system, although its activities on peripheral tissues are responsible for many adverse side effects.
For these reasons, it is very important also to understand the role of morphine in cancer treatment.
The published literature reporting the effect of morphine on tumor growth presents some discrepancies, with reports suggesting that morphine may either promote or inhibit the tumor growth.
It has been also demonstrated that morphine modulates angiogenesis which is important for primary tumour growth, invasiveness, and the development of metastasis.
This review will focus on the latest findings on the role of morphine in the regulation of cancer cell growth and angiogenesis.
American Psychological Association (APA)
Bimonte, Sabrina& Barbieri, Antonio& Palma, Giuseppe& Arra, Claudio. 2013. The Role of Morphine in Animal Models of Human Cancer: Does Morphine Promote or Inhibit the Tumor Growth?. BioMed Research International،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-1003815
Modern Language Association (MLA)
Bimonte, Sabrina…[et al.]. The Role of Morphine in Animal Models of Human Cancer: Does Morphine Promote or Inhibit the Tumor Growth?. BioMed Research International No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-1003815
American Medical Association (AMA)
Bimonte, Sabrina& Barbieri, Antonio& Palma, Giuseppe& Arra, Claudio. The Role of Morphine in Animal Models of Human Cancer: Does Morphine Promote or Inhibit the Tumor Growth?. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-1003815
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003815