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Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats
Joint Authors
Rocha, Aldeíde de Oliveira Batista
Sousa, Liliane de Queirós
Mota, Clélia de Alencar Xavier
Santos, Elane Cristina S.
Diniz, Margareth de Fátima Formiga Melo
da Silva, Marcelo Sobral
Pimenta, Martina Bragante F.
Sá, Rita de Cássia da Silveira e
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The treatment during the embryonic preimplantation phase of Wistar rats with the Pradosia huberi extract did not interfere with the water and feed consumption, as well as upon the body-weight gain.
However, it has expressed a decrease of the uterine implant number, followed by the preimplantation losses at all applied doses (1.22, 6.1, and 30.5 mg/kg), and the number of embryonic resorptions in the two highest doses (6.1 and 30.5 mg/kg).
After the organ weighing (hypophysis, ovaries, and uterus), only the relative weight of the hypophysis was raised at the different doses (1.22, 6.1, and 30.5 mg/kg).
It was concluded that the hydroalcoholic extract of Pradosia huberi compromises the reproductive ability during the embryonic preimplantation phase, suggesting a possible toxic effect upon the reproductive system of Wistar rats.
American Psychological Association (APA)
Rocha, Aldeíde de Oliveira Batista& Sousa, Liliane de Queirós& Mota, Clélia de Alencar Xavier& Santos, Elane Cristina S.& Diniz, Margareth de Fátima Formiga Melo& da Silva, Marcelo Sobral…[et al.]. 2012. Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1003922
Modern Language Association (MLA)
Rocha, Aldeíde de Oliveira Batista…[et al.]. Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1003922
American Medical Association (AMA)
Rocha, Aldeíde de Oliveira Batista& Sousa, Liliane de Queirós& Mota, Clélia de Alencar Xavier& Santos, Elane Cristina S.& Diniz, Margareth de Fátima Formiga Melo& da Silva, Marcelo Sobral…[et al.]. Evaluation of the Toxicity of Pradosia huberi Extract during the Preimplantation in Wistar Rats. BioMed Research International. 2012. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1003922
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003922