Fabrication of Microfibrous and Nano-Microfibrous Scaffolds: Melt and Hybrid Electrospinning and Surface Modification of Poly(L-lactic acid) with Plasticizer
Joint Authors
Park, Won Ho
Yoon, Young Il
Park, Ko Eun
Lee, Seung Jin
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-05
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Biodegradable poly(L-lactic acid) (PLA) fibrous scaffolds were prepared by electrospinning from a PLA melt containing poly(ethylene glycol) (PEG) as a plasticizer to obtain thinner fibers.
The effects of PEG on the melt electrospinning of PLA were examined in terms of the melt viscosity and fiber diameter.
Among the parameters, the content of PEG had a more significant effect on the average fiber diameter and its distribution than those of the spinning temperature.
Furthermore, nano-/microfibrous silk fibroin (SF)/PLA and PLA/PLA composite scaffolds were fabricated by hybrid electrospinning, which involved a combination of solution electrospinning and melt electrospinning.
The SF/PLA (20/80) scaffolds consisted of a randomly oriented structure of PLA microfibers (average fiber diameter = 8.9 µm) and SF nanofibers (average fiber diameter = 820 nm).
The PLA nano-/microfiber (20/80) scaffolds were found to have similar pore parameters to the PLA microfiber scaffolds.
The PLA scaffolds were treated with plasma in the presence of either oxygen or ammonia gas to modify the surface of the fibers.
This approach of controlling the surface properties and diameter of fibers could be useful in the design and tailoring of novel scaffolds for tissue engineering.
American Psychological Association (APA)
Yoon, Young Il& Park, Ko Eun& Lee, Seung Jin& Park, Won Ho. 2013. Fabrication of Microfibrous and Nano-Microfibrous Scaffolds: Melt and Hybrid Electrospinning and Surface Modification of Poly(L-lactic acid) with Plasticizer. BioMed Research International،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1003971
Modern Language Association (MLA)
Yoon, Young Il…[et al.]. Fabrication of Microfibrous and Nano-Microfibrous Scaffolds: Melt and Hybrid Electrospinning and Surface Modification of Poly(L-lactic acid) with Plasticizer. BioMed Research International No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-1003971
American Medical Association (AMA)
Yoon, Young Il& Park, Ko Eun& Lee, Seung Jin& Park, Won Ho. Fabrication of Microfibrous and Nano-Microfibrous Scaffolds: Melt and Hybrid Electrospinning and Surface Modification of Poly(L-lactic acid) with Plasticizer. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-1003971
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003971