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Oral Immunogenicity of Plant-Made Mycobacterium tuberculosis ESAT6 and CFP10
Joint Authors
Uvarova, Elena A.
Belavin, Pavel A.
Permyakova, Natalya V.
Zagorskaya, Alla A.
Nosareva, Olesya V.
Kakimzhanova, Almagul A.
Deineko, Elena V.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Two lines of transgenic carrot plants producing Mycobacterium tuberculosis proteins (ESAT6 and CFP10) have been constructed.
The target proteins are present in carrot storage roots at a level not less than 0.056% of the total storage protein (TSP) for ESAT6 and 0.002% of TSP for CFP10.
As has been shown, oral immunization of mice induces both the cell-mediated and humoral immunities.
These data suggest that the proteins in question are appropriate as a candidate edible vaccine against tuberculosis.
American Psychological Association (APA)
Uvarova, Elena A.& Belavin, Pavel A.& Permyakova, Natalya V.& Zagorskaya, Alla A.& Nosareva, Olesya V.& Kakimzhanova, Almagul A.…[et al.]. 2013. Oral Immunogenicity of Plant-Made Mycobacterium tuberculosis ESAT6 and CFP10. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004000
Modern Language Association (MLA)
Uvarova, Elena A.…[et al.]. Oral Immunogenicity of Plant-Made Mycobacterium tuberculosis ESAT6 and CFP10. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1004000
American Medical Association (AMA)
Uvarova, Elena A.& Belavin, Pavel A.& Permyakova, Natalya V.& Zagorskaya, Alla A.& Nosareva, Olesya V.& Kakimzhanova, Almagul A.…[et al.]. Oral Immunogenicity of Plant-Made Mycobacterium tuberculosis ESAT6 and CFP10. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004000
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004000