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A Sensitive Chemotaxis Assay Using a Novel Microfluidic Device
Joint Authors
Zhang, Chen
Jang, Sunyoung
Amadi, Ovid C.
Shimizu, Koichi
Lee, Richard T.
Mitchell, Richard N.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Existing chemotaxis assays do not generate stable chemotactic gradients and thus—over time—functionally measure only nonspecific random motion (chemokinesis).
In comparison, microfluidic technology has the capacity to generate a tightly controlled microenvironment that can be stably maintained for extended periods of time and is, therefore, amenable to adaptation for assaying chemotaxis.
We describe here a novel microfluidic device for sensitive assay of cellular migration and show its application for evaluating the chemotaxis of smooth muscle cells in a chemokine gradient.
American Psychological Association (APA)
Zhang, Chen& Jang, Sunyoung& Amadi, Ovid C.& Shimizu, Koichi& Lee, Richard T.& Mitchell, Richard N.. 2013. A Sensitive Chemotaxis Assay Using a Novel Microfluidic Device. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004134
Modern Language Association (MLA)
Zhang, Chen…[et al.]. A Sensitive Chemotaxis Assay Using a Novel Microfluidic Device. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1004134
American Medical Association (AMA)
Zhang, Chen& Jang, Sunyoung& Amadi, Ovid C.& Shimizu, Koichi& Lee, Richard T.& Mitchell, Richard N.. A Sensitive Chemotaxis Assay Using a Novel Microfluidic Device. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004134
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004134