![](/images/graphics-bg.png)
Immunomodulatory Effects of Adipose-Derived Stem Cells: Fact or Fiction?
Joint Authors
Leto Barone, Angelo A.
Khalifian, Saami
Lee, W. P. Andrew
Brandacher, Gerald
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Adipose-derived stromal cells (ASCs) are often referred to as adipose-derived stem cells due to their potential to undergo multilineage differentiation.
Their promising role in tissue engineering and ability to modulate the immune system are the focus of extensive research.
A number of clinical trials using ASCs are currently underway to better understand the role of such cell niche in enhancing or suppressing the immune response.
If governable, such immunoregulatory role would find application in several conditions in which an immune response is present (i.e., autoimmune conditions) or feared (i.e., solid organ or reconstructive transplantation).
Although allogeneic ASCs have been shown to prevent acute GvHD in both preclinical and clinical studies, their potential warrants further investigation.
Well-designed and standardized clinical trials are necessary to prove the role of ASCs in the treatment of immune disorders or prevention of tissue rejection.
In this paper we analyze the current literature on the role of ASCs in immunomodulation in vitro and in vivo and discuss their potential in regulating the immune system in the context of transplantation.
American Psychological Association (APA)
Leto Barone, Angelo A.& Khalifian, Saami& Lee, W. P. Andrew& Brandacher, Gerald. 2013. Immunomodulatory Effects of Adipose-Derived Stem Cells: Fact or Fiction?. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004153
Modern Language Association (MLA)
Leto Barone, Angelo A.…[et al.]. Immunomodulatory Effects of Adipose-Derived Stem Cells: Fact or Fiction?. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1004153
American Medical Association (AMA)
Leto Barone, Angelo A.& Khalifian, Saami& Lee, W. P. Andrew& Brandacher, Gerald. Immunomodulatory Effects of Adipose-Derived Stem Cells: Fact or Fiction?. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004153
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004153