Adipose-Derived Mesenchymal Cells for Bone Regereneration: State of the Art
Joint Authors
Barba, Marta
Cicione, Claudia
Bernardini, Camilla
Lattanzi, Wanda
Michetti, Fabrizio
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Adipose tissue represents a hot topic in regenerative medicine because of the tissue source abundance, the relatively easy retrieval, and the inherent biological properties of mesenchymal stem cells residing in its stroma.
Adipose-derived mesenchymal stem cells (ASCs) are indeed multipotent somatic stem cells exhibiting growth kinetics and plasticity, proved to induce efficient tissue regeneration in several biomedical applications.
A defined consensus for their isolation, classification, and characterization has been very recently achieved.
In particular, bone tissue reconstruction and regeneration based on ASCs has emerged as a promising approach to restore structure and function of bone compromised by injury or disease.
ASCs have been used in combination with osteoinductive biomaterial and/or osteogenic molecules, in either static or dynamic culture systems, to improve bone regeneration in several animal models.
To date, few clinical trials on ASC-based bone reconstruction have been concluded and proved effective.
The aim of this review is to dissect the state of the art on ASC use in bone regenerative applications in the attempt to provide a comprehensive coverage of the topics, from the basic laboratory to recent clinical applications.
American Psychological Association (APA)
Barba, Marta& Cicione, Claudia& Bernardini, Camilla& Michetti, Fabrizio& Lattanzi, Wanda. 2013. Adipose-Derived Mesenchymal Cells for Bone Regereneration: State of the Art. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1004262
Modern Language Association (MLA)
Barba, Marta…[et al.]. Adipose-Derived Mesenchymal Cells for Bone Regereneration: State of the Art. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1004262
American Medical Association (AMA)
Barba, Marta& Cicione, Claudia& Bernardini, Camilla& Michetti, Fabrizio& Lattanzi, Wanda. Adipose-Derived Mesenchymal Cells for Bone Regereneration: State of the Art. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1004262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004262