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Chronic Traumatic Encephalopathy and Suicide: A Systematic Review
Joint Authors
Wortzel, Hal S.
Shura, Robert D.
Brenner, Lisa A.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Traumatic brain injury (TBI) is a global health concern, and the recent literature reports that a single mild TBI can result in chronic traumatic encephalopathy (CTE).
It has been suggested that CTE may lead to death by suicide, raising important prevention, treatment, and policy implications.
Thus, we conducted a systematic review of the medical literature to answer the key question: What is the existing evidence in support of a relationship between CTE and suicide? Systematic searches of CTE and suicide yielded 85 unique abstracts.
Seven articles were identified for full text review.
Only two case series met inclusion criteria and included autopsies from 17 unique cases, 5 of whom died by suicide.
Neither studies used blinding, control cases, or systematic data collection regarding TBI exposure and/or medical/neuropsychiatric history.
The identified CTE literature revealed divergent opinions regarding neuropathological elements of CTE and heterogeneity regarding clinical manifestations.
Overall quality of evidence regarding a relationship between CTE and suicide was rated as very low using Grading of Recommendations Assessment, Development and Evaluation Working Group (GRADE) criteria.
Further studies of higher quality and methodological rigor are needed to determine the existence and nature of any relationship between CTE and suicide.
American Psychological Association (APA)
Wortzel, Hal S.& Shura, Robert D.& Brenner, Lisa A.. 2013. Chronic Traumatic Encephalopathy and Suicide: A Systematic Review. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1004282
Modern Language Association (MLA)
Wortzel, Hal S.…[et al.]. Chronic Traumatic Encephalopathy and Suicide: A Systematic Review. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1004282
American Medical Association (AMA)
Wortzel, Hal S.& Shura, Robert D.& Brenner, Lisa A.. Chronic Traumatic Encephalopathy and Suicide: A Systematic Review. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1004282
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004282