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Regenerative Medicine for the Cornea
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Regenerative medicine for the cornea provides a novel treatment strategy for patients with corneal diseases instead of conventional keratoplasty.
Limbal transplantation has been performed in patients with a limbal stem cell deficiency.
This procedure requires long-term immunosuppression that involves high risks of serious eye and systemic complications, including infection, glaucoma, and liver dysfunction.
To solve these problems, ocular surface reconstruction using cultured limbal or oral mucosal epithelial stem cells has been successfully applied to patients.
However, cell sheets must be fabricated in a cell processing center (CPC) under good manufacturing practice conditions for clinical use, and the expenses of maintaining a CPC are too high for all hospitals to cover.
Therefore, several hospitals should share one CPC to standardize and spread the application of regenerative therapy using tissue-engineered oral mucosal epithelial cell sheets.
Consequently, we developed a cell transportation technique for clinical trial to bridge hospitals.
This paper reviews the current status of regenerative medicine for the cornea.
American Psychological Association (APA)
Oie, Yoshinori& Nishida, Kohji. 2013. Regenerative Medicine for the Cornea. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004291
Modern Language Association (MLA)
Oie, Yoshinori& Nishida, Kohji. Regenerative Medicine for the Cornea. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1004291
American Medical Association (AMA)
Oie, Yoshinori& Nishida, Kohji. Regenerative Medicine for the Cornea. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1004291
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004291