Qualitative and Quantitative Hippocampal MRI Assessments in Intractable Epilepsy
Joint Authors
Singh, Paramdeep
Kaur, Rupinderjeet
Saggar, Kavita
Singh, Gagandeep
Kaur, Amarpreet
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aims.
To acquire normative data of hippocampal volumes and T2 relaxation times, to evaluate and compare qualitative and quantitative assessments in evaluating hippocampi in patients with different durations of intractable epilepsy, and to propose an imaging protocol based on performance of these techniques.
Methods.
MRI analysis was done in 50 nonepileptic controls and 30 patients with intractable epilepsy on 1.5T scanner.
Visual assessment and hippocampal volumetry were done on oblique coronal IR/T2W and T1W MP-RAGE images, respectively.
T2 relaxation times were measured using 16-echo Carr-Purcell-Meiboom-Gill sequence.
Volumetric data was normalized for variation in head size between individuals.
Patients were divided into temporal (n=20) and extratemporal (n=10) groups based on clinical and EEG localization.
Results.
In controls, right hippocampal volume was slightly more than the left with no effect of age or gender.
In TLE patients, hippocampal volumetry provided maximum concordance with EEG.
Visual assessment of unilateral pathology concurred well with measured quantitative values but poorly in cases with bilateral pathologies.
There were no significant differences of mean values between extratemporal group and controls group.
Quantitative techniques detected mild abnormalities, undetected on visual assessment.
Conclusions.
Quantitative techniques are more sensitive to diagnose bilateral and mild unilateral hippocampal abnormalities.
American Psychological Association (APA)
Singh, Paramdeep& Kaur, Rupinderjeet& Saggar, Kavita& Singh, Gagandeep& Kaur, Amarpreet. 2013. Qualitative and Quantitative Hippocampal MRI Assessments in Intractable Epilepsy. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004406
Modern Language Association (MLA)
Singh, Paramdeep…[et al.]. Qualitative and Quantitative Hippocampal MRI Assessments in Intractable Epilepsy. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1004406
American Medical Association (AMA)
Singh, Paramdeep& Kaur, Rupinderjeet& Saggar, Kavita& Singh, Gagandeep& Kaur, Amarpreet. Qualitative and Quantitative Hippocampal MRI Assessments in Intractable Epilepsy. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004406
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004406