The Usefulness of Confusion, Urea, Respiratory Rate, and Shock Index or Adjusted Shock Index Criteria in Predicting Combined Mortality andor ICU Admission Compared to CURB-65 in Community-Acquired Pneumonia

Abstract EN

The study aims to assess the usefulness of age-independent criteria CURSI and temperature adjusted CURSI (CURASI) compared to CURB-65 in predicting community-acquired pneumonia (CAP) mortality.

The criteria, CRSI and CRASI, were adapted for use in primary care and compared to CRB-65.

Methods.

A retrospective analysis of a prospectively identified cohort of community-acquired pneumonia inpatients was conducted.

Outcomes were (1) mortality and (2) mortality and/or ICU admission within six weeks.

Results.

95 patients (median age = 61 years) were included.

All three criteria had similar sensitivity in predicting mortality alone, with CURB-65 having slightly higher specificity.

When predicting mortality and/or intensive care admission, CURSI/CURASI showed higher sensitivity and slightly lower specificity.

CRSI and CRASI had higher sensitivity and lower specificity when compared with CRB-65 for predicting both primary and secondary outcomes.

Results for both analyses had P values >0.05.

Conclusions.

In a cohort of younger patients CURSI and adjusted CURSI perform at least as well as CURB-65, with a similar trend for CRSI and adjusted CRSI compared to CRB-65.

Further studies are needed in different age groups and in primary and secondary care settings.