Do Telomeres Adapt to Physiological Stress? Exploring the Effect of Exercise on Telomere Length and Telomere-Related Proteins
Joint Authors
Ludlow, Andrew T.
Roth, Stephen M.
Wohlers, Lindsay M.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-24
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Aging is associated with a tissue degeneration phenotype marked by a loss of tissue regenerative capacity.
Regenerative capacity is dictated by environmental and genetic factors that govern the balance between damage and repair.
The age-associated changes in the ability of tissues to replace lost or damaged cells is partly the cause of many age-related diseases such as Alzheimer's disease, cardiovascular disease, type II diabetes, and sarcopenia.
A well-established marker of the aging process is the length of the protective cap at the ends of chromosomes, called telomeres.
Telomeres shorten with each cell division and with increasing chronological age and short telomeres have been associated with a range of age-related diseases.
Several studies have shown that chronic exposure to exercise (i.e., exercise training) is associated with telomere length maintenance; however, recent evidence points out several controversial issues concerning tissue-specific telomere length responses.
The goals of the review are to familiarize the reader with the current telomere dogma, review the literature exploring the interactions of exercise with telomere phenotypes, discuss the mechanistic research relating telomere dynamics to exercise stimuli, and finally propose future directions for work related to telomeres and physiological stress.
American Psychological Association (APA)
Ludlow, Andrew T.& Wohlers, Lindsay M.& Roth, Stephen M.. 2013. Do Telomeres Adapt to Physiological Stress? Exploring the Effect of Exercise on Telomere Length and Telomere-Related Proteins. BioMed Research International،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1004696
Modern Language Association (MLA)
Ludlow, Andrew T.…[et al.]. Do Telomeres Adapt to Physiological Stress? Exploring the Effect of Exercise on Telomere Length and Telomere-Related Proteins. BioMed Research International No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-1004696
American Medical Association (AMA)
Ludlow, Andrew T.& Wohlers, Lindsay M.& Roth, Stephen M.. Do Telomeres Adapt to Physiological Stress? Exploring the Effect of Exercise on Telomere Length and Telomere-Related Proteins. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1004696
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004696