The Role of Neuropeptides in Suicidal Behavior: A Systematic Review
Joint Authors
Serafini, Gianluca
Pompili, Maurizio
Lindqvist, Daniel
Dwivedi, Yogesh
Girardi, Paolo
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-06
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
There is a growing evidence that neuropeptides may be involved in the pathophysiology of suicidal behavior.
A critical review of the literature was conducted to investigate the association between neuropeptides and suicidal behavior.
Only articles from peer-reviewed journals were selected for the inclusion in the present review.
Twenty-six articles were assessed for eligibility but only 22 studies were included.
Most studies have documented an association between suicidality and some neuropeptides such as corticotropin-releasing factor (CRF), VGF, cholecystokinin, substance P, and neuropeptide Y (NPY), which have been demonstrated to act as key neuromodulators of emotional processing.
Significant differences in neuropeptides levels have been found in those who have attempted or completed suicide compared with healthy controls or those dying from other causes.
Despite cross-sectional associations between neuropeptides levels and suicidal behavior, causality may not be inferred.
The implications of the mentioned studies were discussed in this review paper.
American Psychological Association (APA)
Serafini, Gianluca& Pompili, Maurizio& Lindqvist, Daniel& Dwivedi, Yogesh& Girardi, Paolo. 2013. The Role of Neuropeptides in Suicidal Behavior: A Systematic Review. BioMed Research International،Vol. 2013, no. 2013, pp.1-22.
https://search.emarefa.net/detail/BIM-1004865
Modern Language Association (MLA)
Serafini, Gianluca…[et al.]. The Role of Neuropeptides in Suicidal Behavior: A Systematic Review. BioMed Research International No. 2013 (2013), pp.1-22.
https://search.emarefa.net/detail/BIM-1004865
American Medical Association (AMA)
Serafini, Gianluca& Pompili, Maurizio& Lindqvist, Daniel& Dwivedi, Yogesh& Girardi, Paolo. The Role of Neuropeptides in Suicidal Behavior: A Systematic Review. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-22.
https://search.emarefa.net/detail/BIM-1004865
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004865