The Rabbit as a Model for Studying Lung Disease and Stem Cell Therapy
Joint Authors
Kamaruzaman, Nurfatin Asyikhin
Kardia, Egi
Kamaldin, Nurulain ‘Atikah
Latahir, Ahmad Zaeri
Yahaya, B.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-04
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
No single animal model can reproduce all of the human features of both acute and chronic lung diseases.
However, the rabbit is a reliable model and clinically relevant facsimile of human disease.
The similarities between rabbits and humans in terms of airway anatomy and responses to inflammatory mediators highlight the value of this species in the investigation of lung disease pathophysiology and in the development of therapeutic agents.
The inflammatory responses shown by the rabbit model, especially in the case of asthma, are comparable with those that occur in humans.
The allergic rabbit model has been used extensively in drug screening tests, and this model and humans appear to be sensitive to similar drugs.
In addition, recent studies have shown that the rabbit serves as a good platform for cell delivery for the purpose of stem-cell-based therapy.
American Psychological Association (APA)
Kamaruzaman, Nurfatin Asyikhin& Kardia, Egi& Kamaldin, Nurulain ‘Atikah& Latahir, Ahmad Zaeri& Yahaya, B.. 2013. The Rabbit as a Model for Studying Lung Disease and Stem Cell Therapy. BioMed Research International،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-1004880
Modern Language Association (MLA)
Kamaruzaman, Nurfatin Asyikhin…[et al.]. The Rabbit as a Model for Studying Lung Disease and Stem Cell Therapy. BioMed Research International No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-1004880
American Medical Association (AMA)
Kamaruzaman, Nurfatin Asyikhin& Kardia, Egi& Kamaldin, Nurulain ‘Atikah& Latahir, Ahmad Zaeri& Yahaya, B.. The Rabbit as a Model for Studying Lung Disease and Stem Cell Therapy. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-1004880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004880