Oxidative Stress in the Pathogenesis of Colorectal Cancer: Cause or Consequence?
Author
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-14
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
There is a growing support for the concept that reactive oxygen species, which are known to be implicated in a range of diseases, may be important progenitors in carcinogenesis, including colorectal cancer (CRC).
CRC is one of the most common cancers worldwide, with the highest incidence rates in western countries.
Sporadic human CRC may be attributable to various environmental and lifestyle factors, such as dietary habits, obesity, and physical inactivity.
In the last decades, association between oxidative stress and CRC has been intensively studied.
Recently, numerous genetic and lifestyle factors that can affect an individual's ability to respond to oxidative stress have been identified.
The aim of this paper is to review evidence linking oxidative stress to CRC and to provide essential background information for accurate interpretation of future research on oxidative stress and CRC risk.
Brief introduction of different endogenous and exogenous factors that may influence oxidative status and modulate the ability of gut epithelial cells to cope with damaging metabolic challenges is also provided.
American Psychological Association (APA)
Perše, Martina. 2013. Oxidative Stress in the Pathogenesis of Colorectal Cancer: Cause or Consequence?. BioMed Research International،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004967
Modern Language Association (MLA)
Perše, Martina. Oxidative Stress in the Pathogenesis of Colorectal Cancer: Cause or Consequence?. BioMed Research International No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-1004967
American Medical Association (AMA)
Perše, Martina. Oxidative Stress in the Pathogenesis of Colorectal Cancer: Cause or Consequence?. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-1004967
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004967