The Role of Insula-Associated Brain Network in Touch
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The insula is believed to be associated with touch-evoked effects.
In this work, functional MRI was applied to investigate the network model of insula function when 20 normal subjects received tactile stimulation over segregated areas.
Data analysis was performed with SPM8 and Conn toolbox.
Activations in the contralateral posterior insula were consistently revealed for all stimulation areas, with the overlap located in area Ig2.
The area Ig2 was then used as the seed to estimate the insula-associated network.
The right insula, left superior parietal lobule, left superior temporal gyrus, and left inferior parietal cortex showed significant functional connectivity with the seed region for all stimulation conditions.
Connectivity maps of most stimulation conditions were mainly distributed in the bilateral insula, inferior parietal cortex, and secondary somatosensory cortex.
Post hoc ROI-to-ROI analysis and graph theoretical analysis showed that there were higher correlations between the left insula and the right insula, left inferior parietal cortex and right OP1 for all networks and that the global efficiency was more sensitive than the local efficiency to detect differences between notes in a network.
These results suggest that the posterior insula serves as a hub to functionally connect other regions in the detected network and may integrate information from these regions.
American Psychological Association (APA)
Wei, Pengxu& Bao, Ruixue. 2013. The Role of Insula-Associated Brain Network in Touch. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1004990
Modern Language Association (MLA)
Wei, Pengxu& Bao, Ruixue. The Role of Insula-Associated Brain Network in Touch. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1004990
American Medical Association (AMA)
Wei, Pengxu& Bao, Ruixue. The Role of Insula-Associated Brain Network in Touch. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1004990
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004990