Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering
Joint Authors
Salehi-Nik, Nasim
Amoabediny, Ghassem
Pouran, Behdad
Tabesh, Hadi
Shokrgozar, Mohammad Ali
Haghighipour, Nooshin
Khatibi, Nahid
Anisi, Fatemeh
Mottaghy, Khosrow
Zandieh-Doulabi, Behrouz
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-05
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid the construction of three-dimensional functional tissues.
Since the ultimate aim of a bioreactor is to create a biological product, the engineering parameters, for example, internal and external mass transfer, fluid velocity, shear stress, electrical current distribution, and so forth, are worth to be thoroughly investigated.
The effects of such engineering parameters on biological cultures have been addressed in only a few preceding studies.
Furthermore, it would be highly inefficient to determine the optimal engineering parameters by trial and error method.
A solution is provided by emerging modeling and computational tools and by analyzing oxygen, carbon dioxide, and nutrient and metabolism waste material transports, which can simulate and predict the experimental results.
Discovering the optimal engineering parameters is crucial not only to reduce the cost and time of experiments, but also to enhance efficacy and functionality of the tissue construct.
This review intends to provide an inclusive package of the engineering parameters together with their calculation procedure in addition to the modeling techniques in TE bioreactors.
American Psychological Association (APA)
Salehi-Nik, Nasim& Amoabediny, Ghassem& Pouran, Behdad& Tabesh, Hadi& Shokrgozar, Mohammad Ali& Haghighipour, Nooshin…[et al.]. 2013. Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering. BioMed Research International،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1005073
Modern Language Association (MLA)
Salehi-Nik, Nasim…[et al.]. Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering. BioMed Research International No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-1005073
American Medical Association (AMA)
Salehi-Nik, Nasim& Amoabediny, Ghassem& Pouran, Behdad& Tabesh, Hadi& Shokrgozar, Mohammad Ali& Haghighipour, Nooshin…[et al.]. Engineering Parameters in Bioreactor’s Design: A Critical Aspect in Tissue Engineering. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-1005073
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005073