Measurement of the Silver Ion Concentration in Wound Fluids after Implantation of Silver-Coated Megaprostheses: Correlation with the Clinical Outcome
Joint Authors
Hussmann, B.
Johann, I.
Kauther, M. D.
Landgraeber, S.
Jäger, Marcus
Lendemans, S.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-11
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Tumor patients and patients after traumas are endangered by a reduced immune defense, and a silver coating on their megaprostheses may reduce their risks of infection.
The aim of this study was to determine the silver ion concentration directly measured from the periprosthetic tissue and the influence on the clinical outcome.
Material and Methods.
Silver ions were evaluated in 5 mL wound fluids two days postoperatively and in blood patients 7 and 14 days after surgery using inductively coupled plasma emission spectrometry in 18 patients who underwent total joint replacement with a silver-coated megaendoprosthesis.
Results.
The concentration of silver ions averaged 0.08 parts per million.
Patients who showed an increased silver concentration in the blood postoperatively presented a lower silver concentration in the wound fluids and a delayed decrease in C-reactive protein levels.
There were significantly fewer reinfections and shorter hospitalization in comparison with a group that did not receive a silver-coated megaprosthesis.
Conclusion.
An increased concentration of silver in the immediate surroundings of silver-coated prostheses was demonstrated for the first time in cohorts of patients with trauma or tumors.
An elevated concentration of silver ions in the direct periprosthetic tissue may have reduced the infection rate.
American Psychological Association (APA)
Hussmann, B.& Johann, I.& Kauther, M. D.& Landgraeber, S.& Jäger, Marcus& Lendemans, S.. 2013. Measurement of the Silver Ion Concentration in Wound Fluids after Implantation of Silver-Coated Megaprostheses: Correlation with the Clinical Outcome. BioMed Research International،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1005077
Modern Language Association (MLA)
Hussmann, B.…[et al.]. Measurement of the Silver Ion Concentration in Wound Fluids after Implantation of Silver-Coated Megaprostheses: Correlation with the Clinical Outcome. BioMed Research International No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-1005077
American Medical Association (AMA)
Hussmann, B.& Johann, I.& Kauther, M. D.& Landgraeber, S.& Jäger, Marcus& Lendemans, S.. Measurement of the Silver Ion Concentration in Wound Fluids after Implantation of Silver-Coated Megaprostheses: Correlation with the Clinical Outcome. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-1005077
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005077