Reduction of Orbital Inflammation following Decompression for Thyroid-Related Orbitopathy
Joint Authors
Oh, Sang-Rog
Tung, Jonathan D.
Priel, Ayelet
Levi, Leah
Granet, David B.
Korn, Bobby S.
Kikkawa, Don O.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-06-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
Thyroid-related orbitopathy (TRO) is associated with inflammation, expansion of orbital fat, enlargement of extraocular muscles, and optic neuropathy (ON).
We examined the effects of orbital decompression on the inflammatory and congestive signs of TRO in patients who underwent emergent orbital decompression.
Methods.
This retrospective, consecutive study included patients with ON from TRO who underwent orbital decompression.
Pre- and postoperative orbital inflammatory signs in the operated and nonoperated, contralateral eyes were graded with the 10-item clinical activity score (CAS).
Results.
Thirty-one orbits were included.
Postoperatively, 22 patients and 29 orbits had resolution of ON while the remaining 2 patients had improvement in visual acuity.
Mean preoperative CAS was 9.5 ± 0.4.
At 12 months, postoperative CAS was 2.1 ± 0.6 (P<0.01) in the operated eye and 3.2 ± 0.5 (P<0.05) in the nonoperated, contralateral eye.
Conclusion.
In our series, 94% of orbits had resolution of ON.
There was also a statistically significant postoperative reduction in the CAS in both the operated and nonoperated, contralateral eyes.
This phenomenon may be due to lowered venous congestion, decreased intraorbital pressure, and diminution in inflammatory factors.
American Psychological Association (APA)
Oh, Sang-Rog& Tung, Jonathan D.& Priel, Ayelet& Levi, Leah& Granet, David B.& Korn, Bobby S.…[et al.]. 2013. Reduction of Orbital Inflammation following Decompression for Thyroid-Related Orbitopathy. BioMed Research International،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1005132
Modern Language Association (MLA)
Oh, Sang-Rog…[et al.]. Reduction of Orbital Inflammation following Decompression for Thyroid-Related Orbitopathy. BioMed Research International No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1005132
American Medical Association (AMA)
Oh, Sang-Rog& Tung, Jonathan D.& Priel, Ayelet& Levi, Leah& Granet, David B.& Korn, Bobby S.…[et al.]. Reduction of Orbital Inflammation following Decompression for Thyroid-Related Orbitopathy. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1005132
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005132