Effects of Water Extracts of Graptopetalum paraguayense on Blood Pressure, Fasting Glucose, and Lipid Profiles of Subjects with Metabolic Syndrome
Joint Authors
Lin, Ping-Ting
Yen, Chi-Hua
Chen, Shu-Ju
Liu, Jen-Tzu
Tseng, Yu-Fen
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This study was aimed to investigate the effects of water extracts of Graptopetalum paraguayense (WGP, 4 g/d) on blood pressure, blood glucose level, and lipid profiles in subjects with metabolic syndrome (MS).
Participants with MS (n=54) were randomly assigned to the placebo (n=28) and WGP groups (n=26), and the intervention was administered for 12 weeks.
Systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting glucose (FG), lipid profiles (total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein (HDL-C)), and antioxidant enzymes activities (catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx)) were measured.
Forty-two subjects completed the study (placebo, n=19; WGP, n=23).
FG, SBP, and LDL-C levels were significantly lower and HDL-C level and antioxidant enzymes activities (CAT and SOD) were significantly higher after WGP supplementation.
Blood pressure, FG, and lipid profiles were significantly correlated with antioxidant enzymes activities after supplementation (P<0.05).
The present study demonstrated a significant reduction in blood pressure, blood glucose, and lipid profiles and an increase in antioxidant enzymes activities in subjects with MS after WGP supplementation.
Taken together, the antioxidative capacity of WGP might exert a beneficial effect on MS.
This trial is registered with ClinicalTrials.gov NCT01463748.
American Psychological Association (APA)
Yen, Chi-Hua& Chen, Shu-Ju& Liu, Jen-Tzu& Tseng, Yu-Fen& Lin, Ping-Ting. 2013. Effects of Water Extracts of Graptopetalum paraguayense on Blood Pressure, Fasting Glucose, and Lipid Profiles of Subjects with Metabolic Syndrome. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1005171
Modern Language Association (MLA)
Yen, Chi-Hua…[et al.]. Effects of Water Extracts of Graptopetalum paraguayense on Blood Pressure, Fasting Glucose, and Lipid Profiles of Subjects with Metabolic Syndrome. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1005171
American Medical Association (AMA)
Yen, Chi-Hua& Chen, Shu-Ju& Liu, Jen-Tzu& Tseng, Yu-Fen& Lin, Ping-Ting. Effects of Water Extracts of Graptopetalum paraguayense on Blood Pressure, Fasting Glucose, and Lipid Profiles of Subjects with Metabolic Syndrome. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1005171
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005171