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HBV Induced HCC: Major Risk Factors from Genetic to Molecular Level
Joint Authors
Ayub, Ambreen
Ashfaq, Usman Ali
Haque, Asma
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-07
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Hepatocellular carcinoma (HCC) is a deadly and emerging disease leading to death in Asian countries.
High hepatitis B virus (HBV) load and chronic hepatitis B (CHB) infection increase the risk of developing HCC.
HBV is a DNA virus that can integrate DNA into host genome thereby increase the yield of transactivator protein HBxAg that may deregulate many pathways involving in metabolism of cells.
Several monogenic and polygenic risk factors are also involved in HCC development.
This review summarizes the mechanism involved in HCC development and discusses some promising therapies to make HCC curative.
American Psychological Association (APA)
Ayub, Ambreen& Ashfaq, Usman Ali& Haque, Asma. 2013. HBV Induced HCC: Major Risk Factors from Genetic to Molecular Level. BioMed Research International،Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-1005174
Modern Language Association (MLA)
Ayub, Ambreen…[et al.]. HBV Induced HCC: Major Risk Factors from Genetic to Molecular Level. BioMed Research International No. 2013 (2013), pp.1-14.
https://search.emarefa.net/detail/BIM-1005174
American Medical Association (AMA)
Ayub, Ambreen& Ashfaq, Usman Ali& Haque, Asma. HBV Induced HCC: Major Risk Factors from Genetic to Molecular Level. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-1005174
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005174