Anti-Inflammatory Activity and Composition of Senecio salignus Kunth
Joint Authors
Zavala-Sánchez, Miguel A.
González-Chávez, Marco Martín
Pérez González, Cuauhtemoc
Serrano Vega, Roberto
Pérez-Gutierrez, Salud
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We investigated the anti-inflammatory activity of Senecio salignus.
This medicinal plant is often used in Mexico for the treatment of fever and rheumatism.
Chloroform and methanol extracts of the plant were tested on 12-O-tetradecanoylphorbol-13-acetate- (TPA-) induced edema in mice ears.
The methanol extract of the plant inhibited edema by 36±4.4% compared with the control, while the chloroform extract exhibited an even greater level of inhibition (64.1%).
The chloroform extract was then fractionated, and the composition of the active fraction was determined by GC-MS.
The anti-inflammatory activity of this fraction was then tested on TPA-induced ear edema in mice, and we found that the active fraction could inhibit edema by 46.9%.
The anti-inflammatory effect of the fraction was also tested on carrageenan-induced paw edema in rats at doses of 100 mg/kg; a 58.9±2.8% reduction of the edema was observed 4 h after administration of carrageenan, and the effect was maintained for 5 h.
American Psychological Association (APA)
Pérez González, Cuauhtemoc& Serrano Vega, Roberto& González-Chávez, Marco Martín& Zavala-Sánchez, Miguel A.& Pérez-Gutierrez, Salud. 2013. Anti-Inflammatory Activity and Composition of Senecio salignus Kunth. BioMed Research International،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-1005186
Modern Language Association (MLA)
Pérez González, Cuauhtemoc…[et al.]. Anti-Inflammatory Activity and Composition of Senecio salignus Kunth. BioMed Research International No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-1005186
American Medical Association (AMA)
Pérez González, Cuauhtemoc& Serrano Vega, Roberto& González-Chávez, Marco Martín& Zavala-Sánchez, Miguel A.& Pérez-Gutierrez, Salud. Anti-Inflammatory Activity and Composition of Senecio salignus Kunth. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-1005186
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005186