A Novel Technique for the Assessment of Preoperative Cardiovascular Risk: Reactive Hyperemic Response to Short-Term Exercise
Joint Authors
Schier, Robert
Hinkelbein, Jochen
Marcus, Hanke
Smallwood, Ashley
Correa, Arlene M.
Mehran, Reza
El-Zein, Randa
Riedel, Bernhard
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Perioperative vascular function has been widely studied using noninvasive techniques that measure reactive hyperemia as a surrogate marker of vascular function.
However, studies are limited to a static setting with patients tested at rest.
We hypothesized that exercise would increase reactive hyperemia as measured by digital thermal monitoring (DTM) in association to patients' cardiometabolic risk.
Methods.
Thirty patients (58 ± 9 years) scheduled for noncardiac surgery were studied prospectively.
Preoperatively, temperature rebound (TR) following upper arm cuff occlusion was measured before and 10 minutes after exercise.
Data are presented as means ± SD.
Statistical analysis utilized ANOVA and Fisher’s exact test, with P values <0.05 regarded as significant.
Results.
Following exercise, TR-derived parameters increased significantly (absolute: 0.53 ± 0.95 versus 0.04 ± 0.42∘C, P=0.04, and % change: 1.78 ± 3.29 versus 0.14 ± 1.27 %, P=0.03).
All patients with preoperative cardiac risk factors had a change in TR (after/before exercise, ΔTR) with values falling in the lower two tertiles of the study population (ΔTR <1.1%).
Conclusion.
Exercise increased the reactive hyperemic response to ischemia.
This dynamic response was blunted in patients with cardiac risk factors.
The usability of this short-term effect for the preoperative assessment of endothelial function warrants further study.
American Psychological Association (APA)
Schier, Robert& Hinkelbein, Jochen& Marcus, Hanke& Smallwood, Ashley& Correa, Arlene M.& Mehran, Reza…[et al.]. 2013. A Novel Technique for the Assessment of Preoperative Cardiovascular Risk: Reactive Hyperemic Response to Short-Term Exercise. BioMed Research International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1005230
Modern Language Association (MLA)
Schier, Robert…[et al.]. A Novel Technique for the Assessment of Preoperative Cardiovascular Risk: Reactive Hyperemic Response to Short-Term Exercise. BioMed Research International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1005230
American Medical Association (AMA)
Schier, Robert& Hinkelbein, Jochen& Marcus, Hanke& Smallwood, Ashley& Correa, Arlene M.& Mehran, Reza…[et al.]. A Novel Technique for the Assessment of Preoperative Cardiovascular Risk: Reactive Hyperemic Response to Short-Term Exercise. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-1005230
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1005230